CD177 anticorps (AA 22-161)
Aperçu rapide pour CD177 anticorps (AA 22-161) (ABIN7193297)
Antigène
Voir toutes CD177 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 22-161
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Fonction
- CD177 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human CD177 (AA: 22-161) expressed in E. Coli.
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Isotype
- IgG2b
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- CD177 (CD177 Molecule (CD177))
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Autre désignation
- CD177
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Sujet
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This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
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Poids moléculaire
- 46.4 kDa
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ID gène
- 57126
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UniProt
- Q8N6Q3
Antigène
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