MTA1 anticorps (AA 541-715)

N° du produit ABIN7193370

Cet anticorps anti-MTA1 est un anticorps Souris Monoclonal détectant MTA1 dans WB, ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour MTA1 anticorps (AA 541-715) (ABIN7193370)

Antigène: MTA1 (Metastasis Associated 1 (MTA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MTA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: 6B1E9

Détail du produit anti-MTA1 anticorps

Épitope: AA 541-715

Fonction: MTA1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human MTA1 (AA: 541-715) expressed in E. Coli.

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur MTA1

Antigène: MTA1 (Metastasis Associated 1 (MTA1))

Autre désignation: MTA1

Sujet:

This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

Poids moléculaire: 80.8 kDa

ID gène: 9112

UniProt: Q13330

Pathways: Chromatin Binding