Rubicon anticorps (AA 859-972)

N° du produit ABIN7193445

Cet anticorps anti-Rubicon est un anticorps Souris Monoclonal détectant Rubicon dans ELISA. Adapté pour Humain.

Aperçu rapide pour Rubicon anticorps (AA 859-972) (ABIN7193445)

Antigène: Rubicon (KIAA0226) (KIAA0226)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Rubicon est non-conjugé

Application: ELISA

Clone: 4F5B5

Détail du produit anti-Rubicon anticorps

Épitope: AA 859-972

Fonction: RUBCN Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human RUBCN (AA: 859-972) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Rubicon

Antigène: Rubicon (KIAA0226) (KIAA0226)

Autre désignation: RUBCN

Sujet:

The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Poids moléculaire: 108.6 kDa

ID gène: 9711

UniProt: Q92622

Pathways: Autophagy