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Rubicon anticorps (AA 859-972)

KIAA0226 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 4F5B5 unconjugated
N° du produit ABIN7193445
  • Antigène Voir toutes Rubicon (KIAA0226) Anticorps
    Rubicon (KIAA0226) (KIAA0226)
    Épitope
    • 18
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 859-972
    Reactivité
    • 33
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 32
    • 1
    Souris
    Clonalité
    • 32
    • 1
    Monoclonal
    Conjugué
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Rubicon est non-conjugé
    Application
    • 29
    • 19
    • 14
    • 13
    • 10
    • 9
    • 5
    • 3
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human RUBCN (AA: 859-972) expressed in E. coli.
    Clone
    4F5B5
    Isotype
    IgG1
    Top Product
    Discover our top product KIAA0226 Anticorps primaire
  • Indications d'application
    WB:1:500 - 1:2000, ELISA:1:10000,
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Antigène
    Rubicon (KIAA0226) (KIAA0226)
    Autre désignation
    RUBCN (KIAA0226 Produits)
    Synonymes
    anticorps RUBICON, anticorps 5330403K09, anticorps Kiaa0226, anticorps Rubicon, anticorps mKIAA0226, anticorps RUN and cysteine rich domain containing beclin 1 interacting protein, anticorps KIAA0226, anticorps RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein, anticorps RUBCN, anticorps KIAA0226, anticorps Rubcn
    Sujet

    Description: The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Aliases: SCAR15, RUBICON, KIAA0226

    Poids moléculaire
    108.6 kDa
    ID gène
    9711
    Pathways
    Autophagy
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