POLR2A/RPB1 anticorps (AA 128-258)
Aperçu rapide pour POLR2A/RPB1 anticorps (AA 128-258) (ABIN7193495)
Antigène
Voir toutes POLR2A/RPB1 (POLR2A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 128-258
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Fonction
- POLR2A Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human POLR2A (AA: 128-258) expressed in E. Coli.
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Isotype
- IgG2b
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
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Autre désignation
- POLR2A
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Sujet
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This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
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Poids moléculaire
- 217 kDa
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UniProt
- P24928
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Pathways
- Regulatory RNA Pathways
Antigène
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