WT1 anticorps (AA 1-181)

N° du produit ABIN7193614

Cet anticorps Souris Monoclonal détecte spécifiquement WT1 dans IHC, FACS, WB, ELISA et ICC. Il présente une réactivité envers Humain et Singe.

Aperçu rapide pour WT1 anticorps (AA 1-181) (ABIN7193614)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 7F9E8

Détail du produit anti-WT1 anticorps

Épitope: AA 1-181

Fonction: WT1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human WT1 (AA: 1-181) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200-1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: WT1

Sujet:

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.

Poids moléculaire: 49.2 kDa

UniProt: P19544

Pathways: Tube Formation