Prosaposin anticorps (AA 17-216)

N° du produit ABIN7193617

Cet anticorps Souris Monoclonal détecte spécifiquement Prosaposin dans WB, IHC, ELISA, ICC et FACS. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour Prosaposin anticorps (AA 17-216) (ABIN7193617)

Antigène: Prosaposin (PSAP)

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Prosaposin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 3B4A8

Détail du produit anti-Prosaposin anticorps

Épitope: AA 17-216

Fonction: PSAP Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PSAP (AA: 17-216) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200-1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur Prosaposin

Antigène: Prosaposin (PSAP)

Autre désignation: PSAP

Sujet:

This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Poids moléculaire: 58.1 kDa

UniProt: P07602

Pathways: Positive Regulation of Endopeptidase Activity