IL-10RA anticorps (AA 22-235)

N° du produit ABIN7193871

Cet anticorps anti-IL-10RA est un anticorps Souris Monoclonal détectant IL-10RA dans ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour IL-10RA anticorps (AA 22-235) (ABIN7193871)

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-10RA est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 4D3A9

Détail du produit anti-IL-10RA anticorps

Épitope: AA 22-235

Fonction: CD210 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD210 (AA: 22-235) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur IL-10RA

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Autre désignation: CD210

Sujet:

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Poids moléculaire: 63 kDa

ID gène: 3587

UniProt: Q13651

Pathways: Growth Factor Binding