nectin-3 anticorps (AA 431-549)
Aperçu rapide pour nectin-3 anticorps (AA 431-549) (ABIN715391)
Antigène
Voir toutes nectin-3 (NECTIN3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 431-549
-
Réactivité croisée
- Humain, Souris
-
Homologie
- Rat,Cow,Rabbit
-
Purification
- Purified by Protein A.
-
Immunogène
- KLH conjugated synthetic peptide derived from human Nectin 3
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
Date de péremption
- 12 months
-
-
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
-
Autre désignation
- Nectin 3
-
Sujet
-
Synonyms: CD113, CDw113, DKFZP566B0846, FLJ90624, Nectin-3, Nectin3, Poliovirus receptor related 3, Poliovirus receptor related protein 3, Poliovirus receptor-related protein 3, PPR3, PRR3, PVRL 3, PVRL3, PVRL3_HUMAN, PVRR3.
Background: Nectins are immunoglobulin-like adhesion molecules that interact with afadin. Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin-catenin system in epithelial cells.The nectin/PRR-family consists of four members, nectin-1, -2, -3 and -4. All the members of the nectin family have two or three slice variants. Nectin 3 is mainly expressed in testis and placental tissues and interacts in vivo with both long and short isoforms of afadin.
-
ID gène
- 25945
-
Pathways
- Cell-Cell Junction Organization
Antigène
-