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Recombinant VEGF (Bevacizumab Biosimilar) anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement VEGF (Bevacizumab Biosimilar) dans FACS et in vivo. Il présente une réactivité envers Humain.
N° du produit ABIN7200653

Aperçu rapide pour Recombinant VEGF (Bevacizumab Biosimilar) anticorps (ABIN7200653)

Antigène

VEGF (Bevacizumab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 2
  • 1
  • 1
  • 1
  • 1
Souris

Clonalité

  • 3
  • 3
Monoclonal

Conjugué

  • 6
Cet anticorp VEGF (Bevacizumab Biosimilar) est non-conjugé

Application

  • 4
  • 3
  • 3
  • 3
  • 3
Flow Cytometry (FACS), In vivo Studies (in vivo)
  • Fonction

    Bevacizumab Biosimilar, Human VEGF Monoclonal Antibody

    Specificité

    The monoclonal antibody Bevacizumab biosimilar specifically binds to the human VEGF-A.

    Attributs du produit

    Recombinant Humanized IgG1 Monoclonal Antibody generated from the same parent mouse antibody as ranibizumab.

    Purification

    Protein A affinity column

    Pureté

    > 95% by SDS-PAGE under reducing conditions and HPLC.

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    < 1 EU per 1 mg of the protein by the LAL method.

    Immunogène

    The monoclonal antibody Bevacizumab biosimilar was produced in the bevacizumab biosimilar CHO stable cell line.

    Isotype

    IgG1 kappa
  • Indications d'application

    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by bevacizumab.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, pH 7.4, no stabilizers or preservatives.

    Agent conservateur

    Without preservative

    Conseil sur la manipulation

    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

    Date de péremption

    12 months
  • Antigène

    VEGF (Bevacizumab Biosimilar)

    Classe de substances

    Biosimilar

    Sujet

    Bevacizumab, the humanized anti-VEGF-A monoclonal antibody, produces angiogenesis inhibition and slows the growth of new blood vessels. As the first clinically available angiogenesis inhibitor in the United States, Bevacizumab is used for treatment of certain metastatic cancers, certain lung cancers, renal cancers, ovarian cancers, breast cancers, and glioblastoma multiforme of the brain.

    Vascular endothelial growth factor A (VEGF-A) stimulates angiogenesis in a variety of cancers, including colorectal, lung, breast, glioblastoma, kidney, and ovarian cancers.
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