Recombinant VEGF (Bevacizumab Biosimilar) anticorps
Aperçu rapide pour Recombinant VEGF (Bevacizumab Biosimilar) anticorps (ABIN7200653)
Antigène
Type d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Fonction
- Bevacizumab Biosimilar, Human VEGF Monoclonal Antibody
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Specificité
- The monoclonal antibody Bevacizumab biosimilar specifically binds to the human VEGF-A.
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Attributs du produit
- Bevacizumab, the humanized anti-VEGF-A monoclonal antibody, produces angiogenesis inhibition and slows the growth of new blood vessels. As the first clinically available angiogenesis inhibitor in the United States, Bevacizumab is used for treatment of certain metastatic cancers, certain lung cancers, renal cancers, ovarian cancers, breast cancers, and glioblastoma multiforme of the brain. Vascular endothelial growth factor A (VEGF-A) stimulates angiogenesis in a variety of cancers, including colorectal, lung, breast, glioblastoma, kidney, and ovarian cancers.
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Purification
- Protein A or G affinity column
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Pureté
- >95 % by reducing SDS-PAGE
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogène
- The monoclonal antibody Bevacizumab biosimilar was produced in the bevacizumab biosimilar CHO stable cell line.
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Isotype
- IgG1
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Indications d'application
- ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by bevacizumab.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Buffer
- PBS, pH 7.4, no stabilizers or preservatives.
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Agent conservateur
- Without preservative
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Stock
- 4°C,-20 °C
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Stockage commentaire
- 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
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Date de péremption
- 12 months
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- VEGF (Bevacizumab Biosimilar)
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Autre désignation
- Bevacizumab Biosimilar
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Classe de substances
- Biosimilar
Antigène
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