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Recombinant TNFSF11 (Denosumab Biosimilar) anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement TNFSF11 (Denosumab Biosimilar) dans FACS et in vivo. Il présente une réactivité envers Humain.
N° du produit ABIN7200656

Aperçu rapide pour Recombinant TNFSF11 (Denosumab Biosimilar) anticorps (ABIN7200656)

Antigène

TNFSF11 (Denosumab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 3
  • 1
Souris

Clonalité

  • 4
Monoclonal

Conjugué

  • 3
  • 1
Cet anticorp TNFSF11 (Denosumab Biosimilar) est non-conjugé

Application

  • 3
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), In vivo Studies (in vivo)
  • Fonction

    Denosumab Biosimilar, Human RANKL Monoclonal Antibody

    Specificité

    The monoclonal antibody denosumab biosimilar specifically binds to the human RANKL (RANK ligand) protein.

    Attributs du produit

    Recombinant Humanized IgG2 Monoclonal Antibody.

    Purification

    Protein A affinity column

    Pureté

    > 95% by SDS-PAGE under reducing conditions and HPLC.

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    < 1 EU per 1 mg of the protein by the LAL method.

    Immunogène

    The monoclonal antibody denosumab biosimilar was produced in the denosumab biosimilar CHO stable cell line.

    Isotype

    IgG2 kappa
  • Indications d'application

    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by denosumab.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, pH 7.4, no stabilizers or preservatives.

    Agent conservateur

    Without preservative

    Conseil sur la manipulation

    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

    Date de péremption

    12 months
  • Antigène

    TNFSF11 (Denosumab Biosimilar)

    Classe de substances

    Biosimilar

    Sujet

    Denosumab, a fully human monoclonal antibody, inhibits the RANKL (RANK ligand) protein, the primary signal for bone removal. Denosumab can be used for the treatment of osteoporosis, treatment-induced bone loss, bone metastases, multiple myeloma, and giant cell tumor of bone.
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