Cet anticorps anti-ErbB2/Her2 (Pertuzumab Biosimilar) est un anticorps Souris Monoclonal détectant ErbB2/Her2 (Pertuzumab Biosimilar) dans FACS et in vivo. Adapté pour Humain.
N° du produit ABIN7200658
Aperçu rapide pour Recombinant ErbB2/Her2 (Pertuzumab Biosimilar) anticorps (ABIN7200658)
Antigène
ErbB2/Her2 (Pertuzumab Biosimilar)
Type d'anticorp
Recombinant Antibody
Reactivité
Humain
Hôte
Souris
Clonalité
Monoclonal
Conjugué
Cet anticorp ErbB2/Her2 (Pertuzumab Biosimilar) est non-conjugé
Application
Flow Cytometry (FACS), In vivo Studies (in vivo)
Fonction
Pertuzumab Biosimilar, Human HER2 Monoclonal Antibody
Specificité
The monoclonal antibody pertuzumab biosimilar specifically binds to the human HER2/ErbB-2/c-neu.
Attributs du produit
Recombinant humanized IgG1 Monoclonal Antibody.
Purification
Protein A affinity column
Pureté
> 95% by SDS-PAGE under reducing conditions and HPLC.
Stérilité
0.2 μm filtered
niveau d'endotoxine
< 1 EU per 1 mg of the protein by the LAL method.
Immunogène
The monoclonal antibody pertuzumab biosimilar was produced in the pertuzumab biosimilar CHO stable cell line.
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS, pH 7.4, no stabilizers or preservatives.
Agent conservateur
Without preservative
Conseil sur la manipulation
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
Date de péremption
12 months
Antigène
ErbB2/Her2 (Pertuzumab Biosimilar)
Classe de substances
Biosimilar
Sujet
Pertuzumab, a humanized monoclonal antibody, inhibits HER dimerization and is used for the treatment of HER2-positive metastatic breast cancer, in combination with trastuzumab and docetaxel. By binding to HER2, Pertuzumab inhibits the dimerization of HER2 with other HER receptors, resulting in slowed tumor growth.