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Recombinant ErbB2/Her2 (Pertuzumab Biosimilar) anticorps

Cet anticorps anti-ErbB2/Her2 (Pertuzumab Biosimilar) est un anticorps Souris Monoclonal détectant ErbB2/Her2 (Pertuzumab Biosimilar) dans FACS et in vivo. Adapté pour Humain.
N° du produit ABIN7200658

Aperçu rapide pour Recombinant ErbB2/Her2 (Pertuzumab Biosimilar) anticorps (ABIN7200658)

Antigène

ErbB2/Her2 (Pertuzumab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 1
  • 1
  • 1
Souris

Clonalité

  • 2
  • 1
Monoclonal

Conjugué

  • 3
Cet anticorp ErbB2/Her2 (Pertuzumab Biosimilar) est non-conjugé

Application

Flow Cytometry (FACS), In vivo Studies (in vivo)
  • Fonction

    Pertuzumab Biosimilar, Human HER2 Monoclonal Antibody

    Specificité

    The monoclonal antibody pertuzumab biosimilar specifically binds to the human HER2/ErbB-2/c-neu.

    Attributs du produit

    Recombinant humanized IgG1 Monoclonal Antibody.

    Purification

    Protein A affinity column

    Pureté

    > 95% by SDS-PAGE under reducing conditions and HPLC.

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    < 1 EU per 1 mg of the protein by the LAL method.

    Immunogène

    The monoclonal antibody pertuzumab biosimilar was produced in the pertuzumab biosimilar CHO stable cell line.

    Isotype

    IgG1 kappa
  • Indications d'application

    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, pH 7.4, no stabilizers or preservatives.

    Agent conservateur

    Without preservative

    Conseil sur la manipulation

    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

    Date de péremption

    12 months
  • Antigène

    ErbB2/Her2 (Pertuzumab Biosimilar)

    Classe de substances

    Biosimilar

    Sujet

    Pertuzumab, a humanized monoclonal antibody, inhibits HER dimerization and is used for the treatment of HER2-positive metastatic breast cancer, in combination with trastuzumab and docetaxel. By binding to HER2, Pertuzumab inhibits the dimerization of HER2 with other HER receptors, resulting in slowed tumor growth.
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