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Recombinant ErbB2/Her2 (Pertuzumab Biosimilar) anticorps

Cet anticorps anti-ErbB2/Her2 (Pertuzumab Biosimilar) est un anticorps Humanized Monoclonal détectant ErbB2/Her2 (Pertuzumab Biosimilar) dans FACS et in vivo. Adapté pour Humain.
N° du produit ABIN7200658

Aperçu rapide pour Recombinant ErbB2/Her2 (Pertuzumab Biosimilar) anticorps (ABIN7200658)

Antigène

ErbB2/Her2 (Pertuzumab Biosimilar)

Type d'anticorp

Recombinant Antibody

Reactivité

Humain

Hôte

  • 1
  • 1
Humanized

Clonalité

  • 1
  • 1
Monoclonal

Conjugué

  • 2
Cet anticorp ErbB2/Her2 (Pertuzumab Biosimilar) est non-conjugé

Application

Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité

Research Grade
  • Fonction

    Pertuzumab Biosimilar, Human HER2 Monoclonal Antibody

    Specificité

    The monoclonal antibody pertuzumab biosimilar specifically binds to the human HER2/ErbB-2/c-neu.

    Attributs du produit

    Pertuzumab, a humanized monoclonal antibody, inhibits HER dimerization and is used for the treatment of HER2-positive metastatic breast cancer, in combination with trastuzumab and docetaxel. By binding to HER2, Pertuzumab inhibits the dimerization of HER2 with other HER receptors, resulting in slowed tumor growth.

    Purification

    Protein A or G affinity column

    Pureté

    >95 % by reducing SDS-PAGE

    Stérilité

    0.2 μm filtered

    niveau d'endotoxine

    < 1 EU per 1 mg of the protein by the LAL method

    Immunogène

    The monoclonal antibody pertuzumab biosimilar was produced in the pertuzumab biosimilar CHO stable cell line.

    Isotype

    IgG1
  • Indications d'application

    ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    > 3 mg/mL

    Buffer

    PBS, pH 7.4, no stabilizers or preservatives.

    Agent conservateur

    Without preservative

    Stock

    4°C,-20 °C

    Stockage commentaire

    12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

    Date de péremption

    12 months
  • Antigène

    ErbB2/Her2 (Pertuzumab Biosimilar)

    Autre désignation

    Pertuzumab Biosimilar

    Classe de substances

    Biosimilar
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