Recombinant IgE (Omalizumab Biosimilar) anticorps

N° du produit ABIN7200663

L’anticorps anti-IgE (Omalizumab Biosimilar) Monoclonal Humanized est utilisé pour la détection de IgE (Omalizumab Biosimilar) dans des échantillons de Humain. Il a été validé pour FACS et in vivo.

Aperçu rapide pour Recombinant IgE (Omalizumab Biosimilar) anticorps (ABIN7200663)

Antigène: IgE (Omalizumab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Humanized

Clonalité: Monoclonal

Conjugué: Cet anticorp IgE (Omalizumab Biosimilar) est non-conjugé

Application: Flow Cytometry (FACS), In vivo Studies (in vivo)

Classe de qualité: Research Grade

Détail du produit anti-IgE (Omalizumab Biosimilar) anticorps

Fonction: Omalizumab Biosimilar, Human IgE Monoclonal Antibody

Specificité: The monoclonal antibody Omalizumab specifically binds to the human immunoglobulin E (IgE) free in the blood and interstitial fluid and to membrane-bound form of IgE (mIgE) on the surface of mIgE-expressing B lymphocytes. Unlike an ordinary anti-IgE antibody, omalizumab does not bind to IgE that is already bound by the high affinity IgE receptor (FcεRI) on the surface of mast cells, basophils, and antigen-presenting dendritic cells.

Attributs du produit: Omalizumab is a humanized antibody used to reduce sensitivity to inhaled or ingested allergens, especially in the control of moderate to severe allergic asthma which does not respond to high doses of corticosteroids. Immunoglobulin E (IgE) found in mammals only exists as monomers consisting of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). In addition to immunity to parasites, IgE plays an essential role in type I hypersensitivity, which manifests various allergic diseases, and allergic conditions, such as anaphylactic reactions to certain drugs, bee stings, and antigen preparations used in specific desensitization immunotherapy.

Purification: Protein A or G affinity column

Pureté: >95 % by reducing SDS-PAGE

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1 EU per 1 mg of the protein by the LAL method

Immunogène: The monoclonal antibody Omalizumab was produced in the Omalizumab biosimilar CHO stable cell line.

Isotype: IgG1

Information d'application

Indications d'application: Functional assay, neutralization, blocking, ELISA.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: > 3 mg/mL

Buffer: PBS, pH 7.4, no stabilizers or preservatives.

Agent conservateur: Without preservative

Stock: 4°C,-20 °C

Stockage commentaire: 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.

Date de péremption: 12 months

Détails sur IgE (Omalizumab Biosimilar)

Antigène: IgE (Omalizumab Biosimilar)

Autre désignation: Omalizumab Biosimilar

Classe de substances: Biosimilar