XRN1 anticorps

N° du produit ABIN7232190

Cet anticorps anti-XRN1 Polyclonal Lapin (ABIN7232190) détecte spécifiquement XRN1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour XRN1 anticorps (ABIN7232190)

Antigène: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XRN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-XRN1 anticorps

Fonction: Rabbit Anti-XRN1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of XRN1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human XRN1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur XRN1

Antigène: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Autre désignation: XRN1

Sujet: 5'-3' exoribonuclease 1, Strand-exchange protein 1 homologXRN1 encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 187kD

ID gène: 54464

UniProt: Q8IZH2