ADCK1 anticorps (AA 220-300)

N° du produit ABIN7213484

L’anticorps anti-ADCK1 Polyclonal Lapin est utilisé pour la détection de ADCK1 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour ADCK1 anticorps (AA 220-300) (ABIN7213484)

Antigène: ADCK1 (AarF Domain Containing Kinase 1 (ADCK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADCK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ADCK1 anticorps

Épitope: AA 220-300

Fonction: ADCK1 Polyclonal Antibody

Specificité: ADCK1 Polyclonal Antibody detects endogenous levels of ADCK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human ADCK1 at AA range: 220-300

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur ADCK1

Antigène: ADCK1 (AarF Domain Containing Kinase 1 (ADCK1))

Autre désignation: ADCK1

Sujet: Rabbit Anti-ADCK1 Polyclonal Antibody,ADCK1, Uncharacterized aarF domain-containing protein kinase 1,CABC1 (chaperone activity of bc1 complex-like), also known as COQ8 or ADCK3 (aarF domain-containing protein kinase 3) is a 647 amino acid mitochondrial protein that belongs to the ADCK protein kinase. Ubiquitously expressed with higher expression in heart and skeletal muscle, CABC1 is thought to function as a chaperone in the proper assembly of protein complexes found in the respiratory chain. CABC1 expression is induced both in response to DNA damage and by the tumor suppressor p53. When CABC1 expression is inhibited, p53-induced apoptosis is partially suppressed, suggesting a possible role for CABC1 in tumor suppression. Mutations in the gene encoding CABC1 may be implicated in ubiquinone deficiency which can lead to cerebellar ataxia and seizures. Four isoforms of CABC1 exist due to alternative splicing events. Other members of the ADCK protein kinase family include ADCK1, ADCK2, ADCK4 and ADCK5.,Uncharacterized aarF domain-containing protein kinase 1

ID gène: 57143

UniProt: Q86TW2