Acox2 anticorps (AA 270-350)

N° du produit ABIN7227186

Cet anticorps anti-Acox2 Polyclonal Lapin (ABIN7227186) détecte spécifiquement Acox2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Acox2 anticorps (AA 270-350) (ABIN7227186)

Antigène: Acox2 (Acyl-CoA Oxidase 2, Branched Chain (Acox2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acox2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Acox2 anticorps

Épitope: AA 270-350

Fonction: Rabbit Anti-ACOX2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ACOX2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human ACOX2 protein at AA range: 270-350

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Acox2

Antigène: Acox2 (Acyl-CoA Oxidase 2, Branched Chain (Acox2))

Autre désignation: ACOX2

Sujet: Peroxisomal acyl-coenzyme A oxidase 2, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase, Trihydroxycoprostanoyl-CoA oxidase, THCA-CoA oxidase, THCCoxACOX2 (Acyl-CoA Oxidase 2) is a Protein Coding gene. Diseases associated with ACOX2 include Bile Acid Synthesis Defect, Congenital, 6 and Congenital Bile Acid Synthesis Defect. Among its related pathways are Metabolism and Synthesis of bile acids and bile salts. The product of ACOX2 belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe cognitive disability, and death in children.

Poids moléculaire: 74kD

ID gène: 8309

UniProt: Q99424

Pathways: Monocarboxylic Acid Catabolic Process