AFF4 anticorps (AA 30-110)

N° du produit ABIN7227230

L’anticorps anti-AFF4 Polyclonal Lapin est utilisé pour la détection de AFF4 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour AFF4 anticorps (AA 30-110) (ABIN7227230)

Antigène: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFF4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-AFF4 anticorps

Épitope: AA 30-110

Fonction: Rabbit Anti-AFF4 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of AFF4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human AFF4 protein at AA range: 30-110

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur AFF4

Antigène: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Autre désignation: AFF4

Sujet: AF4/FMR2 family member 4, ALL1-fused gene from chromosome 5q31 protein, Protein AF-5q31, Major CDK9 elongation factor-associated proteinAFF4 (AF4/FMR2 Family Member 4) is a Protein Coding gene. Diseases associated with AFF4 include Chops Syndrome and Lymphoblastic Leukemia. Among its related pathways are Formation of HIV elongation complex in the absence of HIV Tat and Gene Expression. The protein encoded by AFF4 belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving AFF4 and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.

Poids moléculaire: 127kD

ID gène: 27125

UniProt: Q9UHB7