ADH5 anticorps (AA 280-360)

N° du produit ABIN7227222

Cet anticorps anti-ADH5 Polyclonal Lapin (ABIN7227222) détecte spécifiquement ADH5 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ADH5 anticorps (AA 280-360) (ABIN7227222)

Antigène: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADH5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ADH5 anticorps

Épitope: AA 280-360

Fonction: Rabbit Anti-ADHX Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ADHX protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human ADHX protein at AA range: 280-360

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ADH5

Antigène: ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

Autre désignation: ADHX

Sujet: Alcohol dehydrogenase class-3, Alcohol dehydrogenase 5, Alcohol dehydrogenase class chi chain, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH, S-(hydroxymethyl)glutathione dehydrogenaseADH5 (Alcohol Dehydrogenase 5 (Class III), Chi Polypeptide) is a Protein Coding gene. Diseases associated with ADH5 include Methanol Poisoning and Pharyngitis. Among its related pathways are Folate-Alcohol and Cancer Pathway and Metabolism. ADH5 encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to ADH5.

Poids moléculaire: 41kD

ID gène: 128

UniProt: P11766