ALDOB anticorps (AA 80-160)
Aperçu rapide pour ALDOB anticorps (AA 80-160) (ABIN7213558)
Antigène
Voir toutes ALDOB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 80-160
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Fonction
- Rabbit Anti-Aldolase B Polyclonal Antibody
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Specificité
- Aldolase B Polyclonal Antibody detects endogenous levels of Aldolase B protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the Internal region of human Aldolase B at AA range: 80-160
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
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Autre désignation
- Aldolase B
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Sujet
- ALDOB, ALDB, Fructose-bisphosphate aldolase B, Liver-type aldolaseFructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
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Poids moléculaire
- 39kD
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ID gène
- 229
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UniProt
- P05062
Antigène
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