APLP1 anticorps (AA 360-440)

N° du produit ABIN7217668

Cet anticorps Lapin Polyclonal détecte spécifiquement APLP1 dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour APLP1 anticorps (AA 360-440) (ABIN7217668)

Antigène: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APLP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-APLP1 anticorps

Épitope: AA 360-440

Fonction: Rabbit Anti-APLP-1 Polyclonal Antibody

Specificité: APLP-1 Polyclonal Antibody detects endogenous levels of APLP-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human APLP-1 at AA range: 360-440

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur APLP1

Antigène: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Autre désignation: APLP-1

Sujet: APLP1, Amyloid-like protein 1, APLP, APLP-1APLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid-like protein 1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Poids moléculaire: 72kD

ID gène: 333

UniProt: P51693

Pathways: cAMP Metabolic Process