AMH anticorps (AA 380-460)

N° du produit ABIN7229680

Cet anticorps anti-AMH est un anticorps Lapin Polyclonal détectant AMH dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour AMH anticorps (AA 380-460) (ABIN7229680)

Antigène: AMH (Anti-Mullerian Hormone (AMH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMH est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-AMH anticorps

Épitope: AA 380-460

Fonction: MIS Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MIS protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human MIS protein at AA range: 380-460

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur AMH

Antigène: AMH (Anti-Mullerian Hormone (AMH))

Autre désignation: MIS

Sujet: Rabbit Anti-MIS Polyclonal Antibody,Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS,AMH encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.,MIS

Poids moléculaire: observerd band 61kDa

ID gène: 268

UniProt: P03971

Pathways: Negative Regulation of Hormone Secretion