AMH anticorps (AA 380-460)

N° du produit ABIN7229680

Cet anticorps anti-AMH Polyclonal Lapin (ABIN7229680) détecte spécifiquement AMH dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour AMH anticorps (AA 380-460) (ABIN7229680)

Antigène: AMH (Anti-Mullerian Hormone (AMH))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMH est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-AMH anticorps

Épitope: AA 380-460

Fonction: Rabbit Anti-MIS Polyclonal Antibody

Specificité: The antibody detects endogenous levels of MIS protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human MIS protein at AA range: 380-460

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur AMH

Antigène: AMH (Anti-Mullerian Hormone (AMH))

Autre désignation: MIS

Sujet: Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MISAMH encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome.

Poids moléculaire: 61kD

ID gène: 268

UniProt: P03971

Pathways: Negative Regulation of Hormone Secretion