DCAF6 anticorps (AA 245-350) (HRP)

N° du produit ABIN715790

L’anticorps Lapin Polyclonal anti-DCAF6 a été validé pour ELISA, IHC (p) et IHC (fro). Il convient pour détecter DCAF6 dans des échantillons de Humain.

Aperçu rapide pour DCAF6 anticorps (AA 245-350) (HRP) (ABIN715790)

Antigène: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCAF6 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DCAF6 anticorps (HRP)

Épitope: AA 245-350

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human NRIP

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DCAF6

Antigène: DCAF6 (DDB1 and CUL4 Associated Factor 6 (DCAF6))

Autre désignation: NRIP

Sujet:

Synonyms: Androgen receptor complex associated protein, ARCAP, IQ mot and WD repeats 1, IQWD1v MSTP055, Nuclear receptor interaction protein, RP4 745I14.1, DCAF6_HUMAN.

Background: WD-repeat proteins are a large family of eukaryotic proteins coordinating multi-protein complex assemblies. Their role has been implicated in multiple cellular processes including signal transduction, transcriptional regulation, cell cycle control and apoptosis. NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up-regulates their transcriptional activity, thereby functioning as a nuclear receptor co-activator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer, thus indicating a potential therapeutic intervention. Northern Blot analysis detects a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

ID gène: 8204