AIFM3 anticorps (AA 10-90)

N° du produit ABIN7213510

Cet anticorps anti-AIFM3 Polyclonal Lapin (ABIN7213510) détecte spécifiquement AIFM3 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour AIFM3 anticorps (AA 10-90) (ABIN7213510)

Antigène: AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIFM3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-AIFM3 anticorps

Épitope: AA 10-90

Fonction: Rabbit Anti-AIFL Polyclonal Antibody

Specificité: AIFL Polyclonal Antibody detects endogenous levels of AIFL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human AIFL at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur AIFM3

Antigène: AIFM3 (Apoptosis-Inducing Factor, Mitochondrion-Associated, 3 (AIFM3))

Autre désignation: AIFL

Sujet: AIFM3, AIFL, Apoptosis-inducing factor 3, Apoptosis-inducing factor-like proteinAIFL (apoptosis-inducing factor-like), also known as AIFM3 (apoptosis-inducing factor, mitochondrion-associated, 3), is a 605 amino acid protein that localizes to the mitochondrion and contains one rieske domain. Expressed ubiquitously in tissues including liver, thymus, ovary, bone marrow and cerebral cortex, AIFL functions to induce apoptosis, specifically through a caspase-dependent pathway, and may also play a role in the modulation of mitochondrial membrane potential. Multiple isoforms of AIFL exist due to alternative splicing events. The gene encoding AIFL maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.

Poids moléculaire: 67kD

ID gène: 150209

UniProt: Q96NN9

Pathways: Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis