AVEN anticorps (AA 270-350)

N° du produit ABIN7213740

L’anticorps anti-AVEN Polyclonal Lapin est utilisé pour la détection de AVEN dans des échantillons de Humain et Singe. Il a été validé pour WB, ELISA, IF et IHC (p).

Aperçu rapide pour AVEN anticorps (AA 270-350) (ABIN7213740)

Antigène: AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AVEN est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-AVEN anticorps

Épitope: AA 270-350

Fonction: Aven Polyclonal Antibody

Specificité: Aven Polyclonal Antibody detects endogenous levels of Aven protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human Aven at AA range: 270-350

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur AVEN

Antigène: AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))

Autre désignation: Aven

Sujet: Rabbit Anti-Aven Polyclonal Antibody,AVEN, Cell death regulator Aven,AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1's ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute lymphoblastic leukemia (ALL), AVEN expression may be a useful tool in prognosis prediction.,Cell death regulator Aven

ID gène: 57099

UniProt: Q9NQS1