Atrophin 1 anticorps (AA 50-130)
Aperçu rapide pour Atrophin 1 anticorps (AA 50-130) (ABIN7213736)
Antigène
Voir toutes Atrophin 1 (ATN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 50-130
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Fonction
- Rabbit Anti-Atrophin-1 Polyclonal Antibody
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Specificité
- Atrophin-1 Polyclonal Antibody detects endogenous levels of Atrophin-1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from the N-terminal region of human Atrophin-1 at AA range: 50-130
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- Atrophin 1 (ATN1)
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Autre désignation
- Atrophin-1
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Sujet
- ATN1, D12S755E, DRPLA, Atrophin-1, Dentatorubral-pallidoluysian atrophy proteinDentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
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Poids moléculaire
- 130kD
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ID gène
- 1822
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UniProt
- P54259
Antigène
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