ATG4C anticorps (AA 40-120)

N° du produit ABIN7225480

L’anticorps anti-ATG4C Polyclonal Lapin est utilisé pour la détection de ATG4C dans des échantillons de Humain et Singe. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour ATG4C anticorps (AA 40-120) (ABIN7225480)

Antigène: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-ATG4C anticorps

Épitope: AA 40-120

Fonction: Rabbit Anti-Atg4C Polyclonal Antibody

Specificité: Atg4C Polyclonal Antibody detects endogenous levels of Atg4C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human Atg4C at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ATG4C

Antigène: ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))

Autre désignation: Atg4C

Sujet: ATG4C, APG4C, AUTL1, AUTL3, Cysteine protease ATG4C, AUT-like 3 cysteine endopeptidase, Autophagin-3, Autophagy-related cysteine endopeptidase 3, Autophagy-related protein 4 homolog CAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4C (autophagy related 4C cysteine peptidase) encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

Poids moléculaire: 49kD

ID gène: 84938

UniProt: Q96DT6

Pathways: Autophagy