L’anticorps anti-BCL2L12 Polyclonal Lapin est utilisé pour la détection de BCL2L12 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.
BCL2L12
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
RB38701
unconjugated
Indications d'application
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Date de péremption
12 months
Antigène
BCL2L12
(BCL2-Like 12 (Proline Rich) (BCL2L12))
Autre désignation
BCL2L12
Sujet
BCL2L12, BPR, Bcl-2-like protein 12, Bcl2-L-12, Bcl-2-related proline-rich proteinBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome 3. Alternative splicing results in multiple transcript variants.