BCL2L2 anticorps (AA 100-180)

N° du produit ABIN7213788

Cet anticorps anti-BCL2L2 Polyclonal Lapin (ABIN7213788) détecte spécifiquement BCL2L2 dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BCL2L2 anticorps (AA 100-180) (ABIN7213788)

Antigène: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2L2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-BCL2L2 anticorps

Épitope: AA 100-180

Fonction: Rabbit Anti-Bcl-w Polyclonal Antibody

Specificité: Bcl-w Polyclonal Antibody detects endogenous levels of Bcl-w protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human Bcl-w at AA range: 100-180

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BCL2L2

Antigène: BCL2L2 (BCL2-Like 2 (BCL2L2))

Autre désignation: Bcl-w

Sujet: BCL2L2, BCLW, KIAA0271, Bcl-2-like protein 2, Bcl2-L-2, Apoptosis regulator Bcl-WBCL2L2 encodes a member (BCL2 like 2)of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of BCL2L2 in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly (A) binding protein, nuclear 1) gene.

Poids moléculaire: 25kD

ID gène: 599

UniProt: Q92843