DQB2 anticorps

N° du produit ABIN7228290

Cet anticorps Lapin Polyclonal détecte spécifiquement DQB2 dans ELISA et WB. Il présente une réactivité envers Humain.

Aperçu rapide pour DQB2 anticorps (ABIN7228290)

Antigène: DQB2 (DQB) (BoLa Class II Histocompatibility Antigen, DQB*0101 beta Chain (DQB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DQB2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-DQB2 anticorps

Fonction: DQB2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of DQB2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human DQB2 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur DQB2

Antigène: DQB2 (DQB) (BoLa Class II Histocompatibility Antigen, DQB*0101 beta Chain (DQB))

Autre désignation: DQB2

Sujet: Rabbit Anti-DQB2 Polyclonal Antibody,HLA class II histocompatibility antigen, DQ beta 2 chain, HLA class II histocompatibility antigen, DX beta chain, MHC class II antigen DQB2,HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus.,DQB2

Poids moléculaire: observerd band 29kDa

ID gène: 3120

UniProt: P05538