BMP8B anticorps (Internal Region)

N° du produit ABIN7224384

L’anticorps anti-BMP8B Polyclonal Lapin est utilisé pour la détection de BMP8B dans des échantillons de Humain et Souris. Il a été validé pour ELISA, IHC et IF.

Aperçu rapide pour BMP8B anticorps (Internal Region) (ABIN7224384)

Antigène: BMP8B (BMP8) (Bone Morphogenetic Protein 8B (BMP8))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP8B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-BMP8B anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-BMP-8 Polyclonal Antibody

Specificité: BMP-8 Polyclonal Antibody detects endogenous levels of BMP-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human BMP-8

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BMP8B

Antigène: BMP8B (BMP8) (Bone Morphogenetic Protein 8B (BMP8))

Autre désignation: BMP-8

Sujet: BMP8B, BMP8, Bone morphogenetic protein 8B, BMP-8, BMP-8B, Osteogenic protein 2, OP-2, BMP8A, Bone morphogenetic protein 8A, BMP-8ABMP8B (bone morphogenetic protein 8b) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of BMP8B may be downregulated in pancreatic cancer. BMP8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.

ID gène: 656

UniProt: P34820, Q7Z5Y6