BCAS3 anticorps (AA 660-740)

N° du produit ABIN7223322

Cet anticorps Lapin Polyclonal détecte spécifiquement BCAS3 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour BCAS3 anticorps (AA 660-740) (ABIN7223322)

Antigène: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAS3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-BCAS3 anticorps

Épitope: AA 660-740

Fonction: Rabbit Anti-BCAS3 Polyclonal Antibody

Specificité: BCAS3 Polyclonal Antibody detects endogenous levels of BCAS3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human BCAS3 at AA range: 660-740

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BCAS3

Antigène: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Autre désignation: BCAS3

Sujet: BCAS3, Breast carcinoma-amplified sequence 3, GAOB1Rudhira/BCAS3 (Breast Cancer Amplified Sequence 3) is a conserved protein expressed in the embryonic vasculature and malignant tumors. Rudhira is a predicted WD40 domain protein. During mouse development Rudhira is expressed in erythropoietic and angiogenic precursors but not in their differentiated progeny. This transient expression of Rudhira is also seen in normal adult angiogenesis. BCAS3, the human ortholog of Rudhira is 98 % identical and the gene maps to a breakpoint of hematological neoplasms on chromosome 17q23. BCAS3 is also expressed in vascular development in embryoid bodies in vitro and was originally identified as a gene over-expressed in breast cancers. It is reported to be a target of metastasis associated protein-1 (MTA-1). Further BCAS3 expression is also upregulated in grade III and IV glioblastomas where it is misexpressed in the tumor cells.

Poids moléculaire: 100kD

ID gène: 54828

UniProt: Q9H6U6