BUB1B anticorps (AA 310-390)

N° du produit ABIN7213866

Cet anticorps anti-BUB1B Polyclonal Lapin (ABIN7213866) détecte spécifiquement BUB1B dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour BUB1B anticorps (AA 310-390) (ABIN7213866)

Antigène: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BUB1B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-BUB1B anticorps

Épitope: AA 310-390

Fonction: Rabbit Anti-BubR1 Polyclonal Antibody

Specificité: BubR1 Polyclonal Antibody detects endogenous levels of BubR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human BubR1 at AA range: 310-390

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur BUB1B

Antigène: BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))

Autre désignation: BubR1

Sujet: BUB1B, BUBR1, MAD3L, SSK1, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, MAD3/BUB1-related protein kinase, hBUBR1, Mitotic checkpoint kinase MAD3L, Protein SSK1BUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine/threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Poids moléculaire: 130kD

ID gène: 701

UniProt: O60566