CREM anticorps (AA 50-130)

N° du produit ABIN7219666

L’anticorps Lapin Polyclonal anti-CREM a été validé pour WB, ELISA et IHC (p). Il convient pour détecter CREM dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CREM anticorps (AA 50-130) (ABIN7219666)

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREM est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CREM anticorps

Épitope: AA 50-130

Fonction: CREM Polyclonal Antibody

Specificité: CREM Polyclonal Antibody detects endogenous levels of CREM protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human CREM at AA range: 50-130

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CREM

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Autre désignation: CREM

Sujet: Rabbit Anti-CREM Polyclonal Antibody,CREM, cAMP-responsive element modulator, Inducible cAMP early repressor, ICER,CREM encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.,cAMP-responsive element modulator

Poids moléculaire: observerd band 34kDa

ID gène: 1390

UniProt: Q03060

Pathways: Retinoic Acid Receptor Signaling Pathway