CPE anticorps (AA 240-320)
Aperçu rapide pour CPE anticorps (AA 240-320) (ABIN7214314)
Antigène
Voir toutes CPE AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 240-320
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Fonction
- CPE Polyclonal Antibody
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Specificité
- CPE Polyclonal Antibody detects endogenous levels of CPE protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human CPE at AA range: 240-320
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CPE (Carboxypeptidase E (CPE))
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Autre désignation
- CPE
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Sujet
- Rabbit Anti-CPE Polyclonal Antibody,CPE, Carboxypeptidase E, CPE, Carboxypeptidase H, CPH, Enkephalin convertase, Prohormone-processing carboxypeptidase,CPE encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. Carboxypeptidase E may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in CPE are implicated in type 2 diabetes.,Carboxypeptidase E
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Poids moléculaire
- observerd band 53kDa
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ID gène
- 1363
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UniProt
- P16870
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Pathways
- Peptide Hormone Metabolism, Synaptic Membrane
Antigène
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