Caspase 4 p20 (AA 40-120), (Cleaved-Gln81) anticorps

N° du produit ABIN7202048

Cet anticorps Lapin Polyclonal détecte spécifiquement Caspase 4 p20 dans WB, ELISA et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Caspase 4 p20 (AA 40-120), (Cleaved-Gln81) anticorps (ABIN7202048)

Antigène: Caspase 4 p20

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 40-120, Cleaved-Gln81

Fonction: Cleaved-Caspase-4 p20 (Q81) Polyclonal Antibody

Specificité: Cleaved-Caspase-4 p20 (Q81) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-4 p20 protein resulting from cleavage adjacent to Q81.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Caspase-4 p20 at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détail du antigène

Antigène: Caspase 4 p20

Autre désignation: Caspase-4 p20

Sujet: Rabbit Anti-Cleaved-Caspase-4 p20 (Q81) Polyclonal Antibody,CASP4, ICH2, Caspase-4, CASP-4, ICE(rel)-II, Protease ICH-2, Protease TX,CASP4 encodes caspase 4 that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, CASP4 induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.,Caspase-4

ID gène: 837

UniProt: P49662