Caspase 5 p10 anticorps (Cleaved-Ser331)

N° du produit ABIN7212442

Cet anticorps anti-Caspase 5 p10 est un anticorps Polyclonal produit chez le Lapin, détectant Caspase 5 p10 dans WB et ELISA. Convient pour Humain.

Aperçu rapide pour Caspase 5 p10 anticorps (Cleaved-Ser331) (ABIN7212442)

Antigène: Caspase 5 p10

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 5 p10 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Caspase 5 p10 anticorps

Épitope: AA 290-370, Cleaved-Ser331

Fonction: Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

Specificité: Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-5 p10 protein resulting from cleavage adjacent to S331.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human Caspase-5 p10 at AA range: 290-370

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Caspase 5 p10

Antigène: Caspase 5 p10

Autre désignation: Caspase-5 p10

Sujet: Rabbit Anti-Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody,CASP5, ICH3, Caspase-5, CASP-5, ICE(rel)-III, Protease ICH-3, Protease TY,CASP5 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of caspase 5 induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by caspase 5, this process requires Fas-mediated dephosphorylation of Max. The expression of CASP5 is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for CASP5.,Caspase-5

Poids moléculaire: observerd band 10kDa

ID gène: 838

UniProt: P51878