Caspase 6 p18 (AA 120-200), (Cleaved-Asp162) anticorps

N° du produit ABIN7202052

L’anticorps anti-Caspase 6 p18 Polyclonal Lapin est utilisé pour la détection de Caspase 6 p18 dans des échantillons de Rat et Souris. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour Caspase 6 p18 (AA 120-200), (Cleaved-Asp162) anticorps (ABIN7202052)

Antigène: Caspase 6 p18

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 120-200, Cleaved-Asp162

Fonction: Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody

Specificité: Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D162.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of mouse Caspase-6 p18 at AA range: 120-200

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détail du antigène

Antigène: Caspase 6 p18

Autre désignation: Caspase-6 p18

Sujet: Rabbit Anti-Cleaved-Caspase-6 p18 (D162) Polyclonal Antibody,CASP6, MCH2, Caspase-6, CASP-6, Apoptotic protease Mch-2,CASP6 encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme.Caspase 6 is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of CASP6 results in multiple transcript variants that encode different isoforms.,Caspase-6

ID gène: 839

UniProt: P55212