CTNND2 anticorps

N° du produit ABIN7228088

Cet anticorps anti-CTNND2 Polyclonal Lapin (ABIN7228088) détecte spécifiquement CTNND2 dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CTNND2 anticorps (ABIN7228088)

Antigène: CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTNND2 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-CTNND2 anticorps

Fonction: Rabbit Anti-CTND2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CTND2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CTND2 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CTNND2

Antigène: CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))

Autre désignation: CTND2

Sujet: Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, NPRAP, NeurojunginCTNND2 encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 134kD

ID gène: 1501

UniProt: Q9UQB3