CNOT7 anticorps (AA 10-90)

N° du produit ABIN7214270

Cet anticorps anti-CNOT7 Polyclonal Lapin (ABIN7214270) détecte spécifiquement CNOT7 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CNOT7 anticorps (AA 10-90) (ABIN7214270)

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CNOT7 anticorps

Épitope: AA 10-90

Fonction: Rabbit Anti-CNOT7 Polyclonal Antibody

Specificité: CNOT7 Polyclonal Antibody detects endogenous levels of CNOT7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the N-terminal region of human CNOT7 at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CNOT7

Antigène: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Autre désignation: CNOT7

Sujet: CNOT7, CAF1, CCR4-NOT transcription complex subunit 7, BTG1-binding factor 1, CCR4-associated factor 1, CAF-1CCR4-NOT transcription complex subunit 7 encoded by CNOT7 binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of CNOT7 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.

Poids moléculaire: 36kD

ID gène: 29883

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization