CD101 anticorps (Internal Region)

N° du produit ABIN7218704

L’anticorps anti-CD101 Polyclonal Lapin est utilisé pour la détection de CD101 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour CD101 anticorps (Internal Region) (ABIN7218704)

Antigène: CD101

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD101 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD101 anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-CD101 Polyclonal Antibody

Specificité: CD101 Polyclonal Antibody detects endogenous levels of CD101 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human CD101

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CD101

Antigène: CD101

Autre désignation: CD101

Sujet: CD101, EWI101, IGSF2, V7, Immunoglobulin superfamily member 2, IgSF2, Cell surface glycoprotein V7, Glu-Trp-Ile EWI motif-containing protein 101, EWI-101, CD101CD101 (CD101 Molecule) is a Protein Coding gene. Diseases associated with CD101 include langerhans-cell histiocytosis and histiocytosis. Among its related pathways are Innate Lymphoid Cell Differentiation Pathways. Gene Ontology (GO) annotations related to this gene include hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. An important paralog of this gene is PTGFRN. Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.

Poids moléculaire: 130kD

ID gène: 9398

UniProt: Q93033