CD207 anticorps (Internal Region)

N° du produit ABIN7218086

Cet anticorps Lapin Polyclonal détecte spécifiquement CD207 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour CD207 anticorps (Internal Region) (ABIN7218086)

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD207 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CD207 anticorps

Épitope: Internal Region

Fonction: Rabbit Anti-CD207 Polyclonal Antibody

Specificité: CD207 Polyclonal Antibody detects endogenous levels of CD207 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human CD207

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: CD207

Sujet: CD207, CLEC4K, C-type lectin domain family 4 member K, Langerin, CD207C-type lectin domain family 4 member K encoded by CD207 is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.

Poids moléculaire: 38kD

ID gène: 50489

UniProt: Q9UJ71