Cdc14A Phosphatase (Internal Region) anticorps

N° du produit ABIN7225542

Cet anticorps Lapin Polyclonal détecte spécifiquement Cdc14A Phosphatase dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Cdc14A Phosphatase (Internal Region) anticorps (ABIN7225542)

Antigène: Cdc14A Phosphatase

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB)

Détail du produit

Épitope: Internal Region

Fonction: Rabbit Anti-Cdc14a phosphatase Polyclonal Antibody

Specificité: Cdc14a phosphatase Polyclonal Antibody detects endogenous levels of Cdc14a phosphatase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Cdc14a phosphatase

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détail du antigène

Antigène: Cdc14A Phosphatase

Sujet: CDC14A, Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog AThe protein encoded by CDC14A (cell division cycle 14A) is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of CDC14A results in several transcript variants encoding distinct isoforms.

Poids moléculaire: 66kD

ID gène: 8556

UniProt: Q9UNH5