CABLES1 anticorps (AA 530-610)

N° du produit ABIN7213900

L’anticorps anti-CABLES1 Polyclonal Lapin est utilisé pour la détection de CABLES1 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour CABLES1 anticorps (AA 530-610) (ABIN7213900)

Antigène: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CABLES1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CABLES1 anticorps

Épitope: AA 530-610

Fonction: Rabbit Anti-Cables1 Polyclonal Antibody

Specificité: Cables1 Polyclonal Antibody detects endogenous levels of Cables1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the C-terminal region of human Cables1 at AA range: 530-610

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CABLES1

Antigène: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Autre désignation: Cables1

Sujet: CABLES1, CABLES, CDK5 and ABL1 enzyme substrate 1, Interactor with CDK3 1, Ik3-1CABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127). Multiple transcript variants encoding different isoforms have been found for CABLES1.

Poids moléculaire: 67kD

ID gène: 91768

UniProt: Q8TDN4