CIDEB anticorps (AA 60-140)

N° du produit ABIN7214210

Cet anticorps anti-CIDEB est un anticorps Lapin Polyclonal détectant CIDEB dans ELISA, WB, IF et IHC (p). Adapté pour Humain et Souris.

Aperçu rapide pour CIDEB anticorps (AA 60-140) (ABIN7214210)

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEB est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CIDEB anticorps

Épitope: AA 60-140

Fonction: CIDE-B Polyclonal Antibody

Specificité: CIDE-B Polyclonal Antibody detects endogenous levels of CIDE-B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human CIDE-B at AA range: 60-140

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CIDEB

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Autre désignation: CIDE-B

Sujet: Rabbit Anti-CIDE-B Polyclonal Antibody,CIDEB, Cell death activator CIDE-B, Cell death-inducing DFFA-like effector B,Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes and bone marrow.,Cell death activator CIDE-B

Poids moléculaire: observerd band 24kDa

ID gène: 27141

UniProt: Q9UHD4