CDC45 anticorps (AA 90-170)

N° du produit ABIN7227774

L’anticorps anti-CDC45 Polyclonal Lapin est utilisé pour la détection de CDC45 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour CDC45 anticorps (AA 90-170) (ABIN7227774)

Antigène: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC45 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CDC45 anticorps

Épitope: AA 90-170

Fonction: Rabbit Anti-CDC45 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CDC45 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CDC45 protein at AA range: 90-170

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CDC45

Antigène: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Autre désignation: CDC45

Sujet: Cell division control protein 45 homolog, PORC-PI-1The protein encoded by CDC45 was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 62kD

ID gène: 8318

UniProt: O75419

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA