CEP290 anticorps (AA 740-820)
Aperçu rapide pour CEP290 anticorps (AA 740-820) (ABIN7214146)
Antigène
Voir toutes CEP290 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 740-820
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Fonction
- CEP290 Polyclonal Antibody
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Specificité
- CEP290 Polyclonal Antibody detects endogenous levels of CEP290 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human CEP290 at AA range: 740-820
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CEP290 (Centrosomal Protein 290kDa (CEP290))
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Autre désignation
- CEP290
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Sujet
- Rabbit Anti-CEP290 Polyclonal Antibody,CEP290, BBS14, KIAA0373, NPHP6, Centrosomal protein of 290 kDa, Cep290, Bardet-Biedl syndrome 14 protein, Cancer/testis antigen 87, CT87, Nephrocystin-6, Tumor antigen se2-2,CEP290 encodes a protein (centrosomal protein 290) with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in CEP290 have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.,Centrosomal protein of 290 kDa
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Poids moléculaire
- observerd band 290kDa
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ID gène
- 80184
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UniProt
- O15078
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Pathways
- cAMP Metabolic Process, M Phase
Antigène
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