CBLN2 anticorps (AA 130-210)

N° du produit ABIN7214156

Cet anticorps anti-CBLN2 est un anticorps Lapin Polyclonal détectant CBLN2 dans WB et ELISA. Adapté pour Humain, Rat, Souris et Singe.

Aperçu rapide pour CBLN2 anticorps (AA 130-210) (ABIN7214156)

Antigène: CBLN2 (Cerebellin 2 Precursor (CBLN2))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBLN2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CBLN2 anticorps

Épitope: AA 130-210

Fonction: Cerebellin 2 Polyclonal Antibody

Specificité: Cerebellin 2 Polyclonal Antibody detects endogenous levels of Cerebellin 2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human Cerebellin 2 at AA range: 130-210

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CBLN2

Antigène: CBLN2 (Cerebellin 2 Precursor (CBLN2))

Autre désignation: Cerebellin 2

Sujet: Rabbit Anti-Cerebellin 2 Polyclonal Antibody,CBLN2, Cerebellin-2,Cerebellin (CER), which was originally isolated from rat cerebellum, is a hexadecapeptide derived from a larger precursor Cerebellin 1, also designated precerebellin 1 or Cbln1. Four propeptides, Cerebellin 1, Cerebellin 2 (Cbln2), Cerebellin 3 (Cbln3), and Cerebellin 4 (Cbln4), comprise the precerebellin subfamily within the C1q protein family. Cerebellin family members act as transneuronal regulators of synapse development and synaptic plasticity in various brain regions. CER and it metabolite des-Ser1-cerebellin are also expressed in several extra-cerebellar tissues, including adrenal gland. Cerebellin 1, 2 and 3 assemble into homomeric and heteromeric complexes, thereby influencing each other's degradation and secretion. Cerebellin 3 is not able to form homomeric complexes, and can only be secreted upon forming a heteromeric complex with Cerebellin 1. Decreased concentrations of CER has been found in the brain of patients with olivopontocerebellar atrophy (OPCA) and Shy-Drager syndrome, suggesting a role for CER in the pathology of these diseases.,Cerebellin-2

Poids moléculaire: observerd band 24kDa

ID gène: 147381

UniProt: Q8IUK8