CCR5 anticorps (AA 151-200)

N° du produit ABIN7227922

Cet anticorps anti-CCR5 Polyclonal Lapin (ABIN7227922) détecte spécifiquement CCR5 dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CCR5 anticorps (AA 151-200) (ABIN7227922)

Antigène: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CCR5 anticorps

Épitope: AA 151-200

Fonction: CKR-5 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CKR-5

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human CKR-5 protein at AA range: 151-200

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:500-1:200), ELISA (1:10000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur CCR5

Antigène: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Autre désignation: CKR-5

Sujet: Rabbit Anti-CKR-5 Polyclonal Antibody,C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor, CD antigen CD195,CCR5 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of CCR5 have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of CCR5 was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. CCR5 is located at the chemokine receptor gene cluster region. An allelic polymorphism in CCR5 results in both functional and non-functional alleles, the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for CCR5.,CKR-5

Poids moléculaire: observerd band 40kDa

ID gène: 1234

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size